Nguyen Quan H.

My research focuses on integrating single-cell spatiotemporal data with large-scale population genomics data to find causal relationships between DNA variants, gene expression and diseases. Using machine learning approaches to analyse multidimensional sequencing and imaging data, I aim to computationally reconstruct intrinsic and extrinsic cellular regulatory networks underlying cancer heterogeneity. The systematic understanding of regulatory networks and biomarkers specific to individuals and cell types will contribute to early disease diagnosis, targeted drug discovery and precision medicine.